Orelli: I think a pharma that wanted a lot of cash flow, but also wanted to boost up their pipeline, Vertex probably has more external deals than it has internal candidates. The management team has been involved in thirteen different acquisitions. I originally heard in March of last year that AcelRx was being "shopped around" when the stock was trading under $5 a share. Seagen has quite a few oncology drugs that would work well with the Bristol-Myers drugs. Places you can follow Scott are: www.stockmatusow.com www.twitter.com/StockMatusow @StockMatusow http://www.facebook.com/TheScottMatusowShow Places to follow Dan are: https://twitter.com/biosleuth. The company is leading the translation of RNA interference (RNAi) to develop treatments for rare genetic, cardio-metabolic, hepatic infectious and central nervous system/ocular diseases. Financial Market Data powered by FinancialContent Services, Inc. All rights reserved. Best Penny Stocks . The acquisition will provide Sanofi access to Amunix Pro-XTEN, XPAT and XPACT technology, complementing Sanofis existing R&D platforms. Brian Orelli: Maybe every biotech in my portfolio, I'd love for each and every one of them to be taken out for a substantial premium. FTX Fooled the World. Shockwave Medical, Inc. (NASDAQ: SWAV), a pioneer in the development of Intravascular Lithotripsy (IVL) to treat severely calcified cardiovascular disease, today announced it has entered into a definitive agreement to acquire Neovasc Inc. (NASDAQ,TSX:NVCN), a company focused on the minimally invasive treatment of refractory angina. Type a symbol or company name. The uptake of all these products has been good. When the symbol you want to add appears, add it to My Quotes by selecting it and pressing Enter/Return. This conference call is no longer online, but the. Then I'll throw one more out -- Vertex (VRTX 3.67%) buying CRISPR Therapeutics (CRSP 3.66%). Going by the average analysts price target, compiled by TipRanks, Alnylam shares have over 28% upside potential. These biopharma companies could end up as attractive buyout targets in 2022. In addition, the Americans have multiple clinical-stage programs in immuno-oncology and regenerative medicine that could provide new assets for big pharmaceutical companies. You can see the complete list of todays Zacks #1 Rank (Strong Buy) stocks here. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. Pharma giant Pfizer recently announced that it will acquire Arena. Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. This management team has time and time again sold companies for nice premiums. 1. Is this happening to you frequently? In case of a buyout, investors often benefit of a massive premium. Total consideration can reflect both cash and equity offered upfront in exchange for the acquired companys shares, but deals in which the upfront payment was not specified, or was less than $50 million, were not included. Medarex bought out GenPharm for $65M. The first few months lived up to expectations: All of the top 10 M&A deals of January-June 2018 exceeded $1.5 billion, paced by the completion of Bayer's $63 billion buyout of Monsanto . 2. BioMarin remains on track to submit a Biologics License Application for Valoctocogene roxaparvovec to the FDA by the end of this year. Considering its massive potential, Axsome Therapeutics it is likely to be ranked high on the shopping list of many large pharmaceutical companies for possible acquisition. That's right -- they think these 10 stocks are even better buys. ALNY also has a deep pipeline with six product candidates in late-stage development. 1985 - 2023 BioSpace.com. No. M&A deal flow dwindled in 2021, reflecting stricter antitrust laws. After a rather bumpy start with disappointing sales numbers in 2019 and 2020, CAPLYTA net product revenues for the second quarter 2022 showed a 190% increase as compared to the same period in 2021 and a 58% increase over the first quarter 2022. While Some Have Learned From It, Others Wont. In this year's M&A deals, most of the acquisition targets were those that were involved in developing cancer drugs or gene therapies. Later, Bristol-Myers Squibb for $2.4B. And how much are they willing to spend? According to a Wall Street Journal report, the companies are in talks regarding a possible acquisition deal. Making the world smarter, happier, and richer. Sold Pharsight Corporation to Tripos International: Mr. Rosen served on the Board of Directors of Pharsight Corporation. Get biopharma news like this in your inbox daily. Copyright Given that the FDA is yet to approve a NASH drug, it is worth taking a risk with this one-trick pony. Oncology-focused biopharma Mirati (NASDAQ:MRTX) is developing a class of drugs called KRAS inhibitors. Example: +water -Europe A company with an approved cancer drug for two different indications and a very promising clinical research pipeline with a market capitalization of only $183.3 million? I am not receiving compensation for it. Sold Tercica to Ipsen: Mr. King served as President and General Manager of Tercica. However, the Company has turned down Elliott's recommendation. I'm thinking Intellia (NASDAQ: NTLA) potentially being acquired by Regeneron (NASDAQ: REGN), and CRISPR Therapeutics (NASDAQ: CRSP) potentially being acquired by Vertex Pharmaceuticals. The following seven biotech stocks could end up as M&A targets in 2022: Alnylam (NASDAQ:ALNY) may have faced a setback recently following an extension to the review period for its Vutisiran, a next-gen RNAi therapeutic candidate, but it still has one of the most exciting pipelines. Clovis Oncology is a commercial-stage biotechnology company whose lead drug is Rubraca, indicated for ovarian cancer. The key factors for a successful M&A lie in targeting deals in or close to core business, selecting deals in attractive market segments, targeting deals where the acquirer can add value and taking a solid post-acquisition value creation approach". Learn More. These apart, updates on vaccines for COVID-19 continue to grab the limelight as the world at large is in dire need of the same to combat the . Alnylams commercial RNAi therapeutic products are Onpattro (patisiran), Givlaari (givosiran), Oxlumo (lumasiran), as well as Leqvio (inclisiran), with partner Novartis, which has obtained global rights to develop, manufacture and commercialize inclisiran under a license and collaboration agreement. Dear MULN Stock Fans, Brace Yourself for a Reverse Stock Split, 5 Under-the-Radar Penny Stocks With 100% Upside Potential, 3 Stocks Set to Soar When the Bears Get Short-Squeezed, 3 Troubled Tech Stocks to Buy For The Long Haul, 3 AI Stocks That Will Make You Amazingly Rich in 10 Years, Attractive & promising pipeline/technology. Let's take a look at some of the biotech companies that have been in the acquisition crosshairs for quite some time. It's a virtual certainty that Otrexup will be approved, so we look for an acquisition to occur shortly afterwards. It was also approved in the EU. Rumors. Source: Mongkolchon Akesin / Shutterstock.com, 7 Potential Biotech Stocks Buyout Targets in 2022, 5 Hypergrowth Stocks With 10X Potential in 2023, M&A momentum is expected to pick up in 2022, to use M&A and partnerships to mitigate the impact of patent cliffs, announced a deal to buy Dicerna, also a RNAi therapeutic company, lnylam shares have over 28% upside potential, average analysts price target compiled by, Recent Layoffs Dont Change the Story for GOOG Stock, Louis Navellier and the InvestorPlace Research Staff. A number of clinical trials with Rubraca in various other indications say, prostate, breast, gastroesophageal, pancreatic, and lung cancers are underway or are expected to be initiated in the near-term. The Company submitted a Marketing Authorization Application to the. If they can get taken out by even higher prices, I think that would be great for the investors. According to a report by Implement Consulting Group, a Scandinavian consultancy, "on average only 62% of the M&A deals are successful. 5 min read Mergers & acquisitions (M&A) are back in focus in the biotech sector after a tepid run in the last couple of years. Intercept Pharma(NASDAQ:ICPT), a company focused on non-viral liver diseases, is a risky M&A target because it is a one-trick pony. The average deal size also shrank from the historical mean of $4.3 billion to $2.8 billion. Capsa Healthcare, a leading innovator in healthcare delivery solutions for hospitals, long-term care, and retail pharmacy providers, announced the acquisition of Tryten Technologies Inc., a designer and manufacturer of lightweight, easy to maneuver mobile cart solutions. Scott is an independent investor/writer/trader and team leader of StockMatusow.com. The post-operative pain market in the United States, Europe, and Japan has been growing steadily over the last few years and is expected to reach $6.5 billion by 2018. The mergers and acquisitions included in the database are limited by certain criteria, namely that they must be for an entire company not for product licensings, options to acquire or for partial equity stakes. Therefore, there are always lots of buyout rumors in the news about potential biotech takeover targets. Therefore, leading companies such as CRISPR Therapeutics, Intellia Therapeutics, or Editas Medicine might catch the eye of large pharmaceutical companies trying to step into this field and complement their pipeline with CRISPR/Cas9 technology. Last month, Adaptimmune announced that SPEARHEAD-1 trial evaluating afamitresgene autoleucel (afami-cel, formerly ADP-A2M4) in patients with advanced synovial sarcoma or myxoid/round cell liposarcoma (MRCLS) will meet its primary endpoint and data will be used to support biologics license application (BLA) filing for afami-cel next year. To read this article on Zacks.com click here. Using these acquired allowed for him to completely divest his own and family's money near the top of the market before the 2008 financial crisis. Leading gene-editing biotechs CRISPR Therapeutics and Intellia are likely to be acquired at some point. The companys cell therapy candidates include Specific Peptide Enhanced Affinity Receptor (SPEAR) T-cells, which use genetically engineered T-cell receptors, next-generation Tumor Infiltrating Lymphocytes (TiLs) where a patients own T-cells are co-administered with next-generation technology, and HLA-independent TCRs (HiTs) where surface proteins are targeted independently of the peptide-HLA complex. We at Biotech Investments expect that pace to continue for the remainder of 2022. Sales of Vascepa have been growing, and in October of this year, an independent drug price watchdog group, Institute for Clinical and Economic Review (ICER), released a report that shows Vascepa as cost-effective for CV risk reduction. Markets. While the management does everything possible to stabilize the financial situation of the company, it noted in the last earnings release that it is seeking ways to raise additional capital, which could include licensing out some of its pipeline assets such as its lead clinical candidate FAP-2286, a potential treatment for advanced solid tumors. The pipeline progress has been encouraging. CRISPRs lead product candidate, CTX001, is an investigational, autologous, gene-edited hematopoietic stem cell therapy that is being evaluated for the treatment of transfusion-dependent beta thalassemia (TDT) and severe sickle cell disease (SCD). Speights: Now, Brian, I'm going to agree with you on every point you just made. 12. If you have an ad-blocker enabled you may be blocked from proceeding. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. Moreover, companies investing in mRNA technology are gaining a lot of attention, given the success of the technology in the development of COVID-19 vaccines. Mergers & Acquisitions (M&As) are back in focus in the biotech sector as Merck MRK recently acquired Acceleron Pharma for $180 per share in cash for an approximate total equity value of $11.5 . Making the world smarter, happier, and richer. 13. The rumors died down after Novartis announced in early January another collaboration with Alnylam for developing targeted therapies to restore liver function. Below are the most notable members and their respective acquisition activity: 1. RTTNews->. Sarepta (NASDAQ:SRPT) is a precision medicine company developing therapies to treat rare diseases. You'll now be able to see real-time price and activity for your symbols on the My Quotes of Nasdaq.com. From it, Others Wont product candidates in late-stage development Tercica to Ipsen: Mr. Rosen served the! 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Some of the biotech companies that have been in the news about potential takeover. 2021, reflecting stricter antitrust laws flow dwindled in 2021, reflecting stricter antitrust laws King served as President General...